Territories
Treatments

Evrysdi – Risdiplam

Link to more information

Available:

Northwest Territories is funding EvrysdiⓇ (risdiplam) effective January 19th 2023. Criteria for funding is not public but expected to be aligned with CADTH . Criteria generally follows NIHB funding criteria given their overlap in patients.

Spinraza – Nusinersen

Available:

Pediatric:

Initiation Criteria
1. Pre-symptomatic patients with 2 or 3 copies of the SMN2 gene,
OR
2. Had the disease for <6 months, 2 copies of SMN2, and symptom onset after the first week after birth and on, or before seven months of age.
OR
3. Patients under the age of 18 with symptom onset > 6 months of age, and never achieved the ability to walk independently. †

Stopping Criteria
1. For those pre-symptomatic at initiation: no improvement/maintenance on HINE-2, CHOP INTEND, or HFMSE, OR
2. For those symptomatic at initiation: no maintenance in HINE-2, CHOP INTENT, or HFMSE, OR
3. Permanent invasive ventilation required

Adult:

“Funding requests for Type 2 and 3 patients 18 years of age and over, as well as Type 2 and 3 patients who have achieved the ability to walk independently will be considered on a case-by-case basis.”

Zolgensma – Onasemnogene abeparvovec

Available:

No information available at this time.